2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis : The Lancet Infectious Diseases

2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis : The Lancet Infectious Diseases

Findings

Worldwide in 2008, diarrhoea attributable to rotavirus infection resulted in 453 000 deaths (95% CI 420 000—494 000) in children younger than 5 years—37% of deaths attributable to diarrhoea and 5% of all deaths in children younger than 5 years. Five countries accounted for more than half of all deaths attributable to rotavirus infection: Democratic Republic of the Congo, Ethiopia, India, Nigeria, and Pakistan; India alone accounted for 22% of deaths (98 621 deaths).

 

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Kit rotavirus@ceeramTools^™

Catalogue References :
Kit rotavirus (assay) KHRV for Clinical samples
Kit rotavirus (assay) KRV for Food & Environmental samples

responsible for most of viral gastroenteritis outbreaks

Rotaviruses are non enveloped, double strand RNA viruses. These viruses are responsible for the majority of gastroentiritis in children. In adults, infections due to rotavirus are underestimated and sometimes asymtomatic. The large majority of gastroenteritis are due to group A rotavirus. Their mode of transmission is via the feco-oral route. After excretion in human stool, due to their structural properties, rotavirus can resist to different physical and chemical treatments.

ROTAVIRUS food poisoning

Adsorbed on particles, they can survive in different kind of environment for a long period. Food can be contaminated by a food-handler during the various stages of food production or via the environment. Thanks to their structural properties, rotaviruses can persit to different food processes. The consumption of contaminated food can lead to outbreaks in population.

methods of choice for RV detection

The diagnostic by cellular culture or ELISA is not adapted to the detection of rotavirus in environmental or food samples. Molecular techniques (real time RT-PCR) are the methods of choice for rotavirus detection after extraction and viral RNA purification from the sample.

CeeramTools Molecular Detection System (Test Kits) also available for :

Kit MengoVirus -­ Kit Norovirus GI -­ Kit Enterorivus -­ Kit Astrovirus -­ Kit Adenovirus -­ Kit HepatitisA - Kit Hepatitis E - Kit AichiVirus - Kit Circovirus - Kit Brachyspira -­ Kit Cryptosporidium - Kit Giardia - Kit Norovirus GII